So, those damn side buttons are causing you to lose a lot of work? X Mouse is one option but tends to stop working after a while. Another option, which I'm using right now, is Mouse Manager and this video walks you through the process of using. I hate these things as I'm not using my mouse for gaming and I hear a lot of gamers also don't like the side buttons because they don't use them while gaming. Microsoft hasn't caught on to this tech which has been around for more than a decade now and provided a way to turn the side buttons off so we have to rely on others to do it for them.
realityripple.com/Software/Applications/Mouse-Manager/